3 November 2021

Analytical Chemistry

MORNING SESSION (9:15 - 12:25 CET)

Chairs:
Nunzia Iaccarino, University of Naples Federico II
Stefano Cinti, University of Naples Federico II

9:15 - 9:20

Institutional welcome: Prof. Angela Zampella, Dean of the Dept. of Pharmacy, University of Naples Federico II (Italy)

9:20 - 10:05

Plenary Lecture (40 + 5min Q/A): Prof. Luigi Mondello, University of Messina (Italy), "Innovative advanced analytical methods in biomedical sciences"

10:05 - 10:35

Keynote Speaker (25 + 5min Q/A): Prof. Bekzod Khakimov, University of Copenhagen (Denmark), "Human blood lipoprotein predictions from 1H NMR spectra: protocol, model performances and cage of covariance"

10:35 - 10:50

Oral Comm. 1 (12 + 3min Q/A)

Giovanni Ventura, University of Bari Aldo Moro (Italy), "AllerT: an automated workflow to identify putative food allergenic proteins of edible insects"

10:50 - 11:05

Oral Comm. 2 (12 + 3min Q/A)

Simona Ranallo, University of Rome Tor Vergata (Italy) and UCSB (US), "Electrochemical DNA-based platform for the multiplexed detection of clinically relevant antibodies"

11:05 - 11:20
Break

11:20 - 11:35

Oral Comm. 3 (12 + 3min Q/A)

11:35 - 11:50

Oral Comm. 4 (12 + 3min Q/A)

Jerro Saidykhan, University of the West of England Bristol (UK), "Paper-based lateral flow device for measuring fibrinogen in human plasma", 

11:50 - 12:05

Oral Comm. 5 (12 + 3min Q/A)

Federico Fanti, University of Teramo (Italy), "Screening and quantitative analysis of short chain fatty acids by means SPE-HPLC-ESI-MS/MS"

12:05 - 12:25
4 x Short Comm. (Slide&Talk) (5min, no Q/A)

Vincenzo Mazzaracchio, University of Rome Tor Vergata (Italy), "A carbon Black-TiO2/KuQuinone screen-printed photoelectrochemical biosensor for ethanol detection in wine samples"

Giuseppe Arrabito, University of Palermo (Italy), "Ink depletion-free printing of phospholipids micro-patches"

Giuliana Siragusa, University of Verona (Italy), "Super SILAC-based mass spectrometry analysis of histone modifications in progressively de-differentiated cancer stem cells derived from pancreatic ductal adenocarcinoma cell lines"

Fulden Ulucan Karnak, Ege University (Turkey), "Nanobiosensor development for cancer diagnosis"

4 November 2021

Medicinal Chemistry

MORNING SESSION (9:30 - 12:30 CET)

Chairs:
Stefano Tomassi, University of Naples Federico II
Sveva Pelliccia, University of Naples Federico II

9:30 - 10:15

Plenary Lecture (40 + 5min Q/A): Prof. Amedeo Caflisch, University of Zurich (Switzerland), "1,4,9-Triazaspiro[5.5]undecan-2-one derivatives as potent and selective METTL3 inhibitors"

10:15 - 10:45

Keynote Speaker (25 + 5min Q/A): Prof. Nir London, Weizmann Research Institute (Israel), "Teaching acrylamides new tricks"

10:45 - 11:00
Oral Comm. 1 (12 + 3min Q/A)

Giulio Poli, University of Pisa (Italy), "Novel cell-active PIN1 inhibitor identified through pharmacophore-driven virtual screening"

11:00 - 11:15
Oral Comm. 2 (12 + 3min Q/A)

Simona Musella, University of Salerno (Italy), "Design, Synthesis and biological evaluation of a dual acting SARS-CoV-2 proteases inhibitor agent"

11:15 - 11:30
Break

11:30 - 11:45
Oral Comm. 3 (12 + 3min Q/A)

Antonella Messore, Sapienza University of Rome (Italy), "Discovery of non-DKA derivatives inhibitors of the HIV-1 Ribonuclease H function of reverse transcriptase"

11:45 - 12:00
Oral Comm. 4 (12 +3min Q/A)

Piermichele Kobauri, University of  Groningen (Netherlands), "Rational design of light-controlled bioactive compounds for photopharmacology"

12:00 - 12:15
Oral Comm. 5 (12 + 3min Q/A)

Carmen Cerchia, University of Naples Federico II (Italy), "Sulfonimide and amide derivatives as novel PPAR-alpha  antagonists"

12:15 - 12:30
3 x Short Comm. "Slide&Talk" (5min, no Q/A)

Lorenzo Baldini, University of Firenze (Italy), "Design of dual peptidomimetic gelatinase/integrin inhibitors for tumor angiogenesis targeting"

Sara La Manna, University of Naples Federico II (Italy), "New SOCS1 cyclic peptidomimetics: from engineering to functional evaluation"

Diego Garcia Jiminez, University of Torino (Italy), "PROTACs: solubility and computed polarity"

Alice Della Valle, University of Chieti Gabriele D' Annunzio (Italy), "Synthesis and characterization of linear peptides analogues of endomorphine-2 and Met/Leu-enkephalin containing a Freidinger gamma-lactam"

Salvatore Galati, University of Pisa (Italy), "structure-based analysis of machine learning predictions for isoform-selective carbonic anhydrase inhibitors"

Giulia De Soricellis, University of Milan (Italy), "Bulkiness and tryptophan: the keystone for Pt(II) and Ir(III) complexes to hit the target of bioimaging and photodynamic therapy?"

5 November 2021

Pharmaceutical Technology & Drug Delivery

MORNING SESSION (9:30 - 12:30 CET)

Chairs:

Claudia Conte, University of Naples Federico II

Gabriella Costabile, University of Naples Federico II

9:30 - 10:15

Plenary Lecture (40 + 5min Q/A): Prof. Cameron Alexander, University of Nottingham (UK), "Polymer therapeutics - from oncology to vaccines"

10:15 - 10:45

Keynote Speaker (25 + 5min Q/A): Prof. Maria de la Fuente Freire,

Oncomet Oncologia Médica Traslacional (Spain), "DIVERSA technologies, from the idea to the market"

Oral Comm. 1 (12 + 3min Q/A)

Giulia Chindamo, University of Torino (Italy), "Curcumin-loaded anticancer lipid nanoparticles design to overcome multi-drug resistance in triple negative breast cancer"

11:00 - 11:15

Oral Comm. 2 (12 + 3min Q/A)

Giovanni Del Poggetto, IPCB-CNR (Italy), "PEGylated cationic nanoassemblies based on triblock copolymers to combine siRNA therapeutics with anticancer drugs"

11:15 - 11:30
Break

11:40 - 11:55

Oral Comm. 3 (12 + 3min Q/A)

Carlo Diaferia, University of Naples Federico II (Italy), "Doxorubicin delivery mediated by peptide-based hydrogels and nanogels"

11:55 - 12:10
Oral Comm. 4 (12 + 3min Q/A)

Sameh El Sayed, University of Birmingham (UK), "Enzyme-degradable polyion-complex nanoparticles for antimicrobial delivery"

12:10 - 12:30

4 x Short Comm. "Slide&Talk" (5min, no Q/A)

Greta Avancini, University of Padova (Italy), "Mesenchymal stem cells membranes camouflaged TPCS2a nanoparticles for targeted photodynamic therapy"

Sara Demartis, University of Sassari (Italy), "Rose bengal loaded 3D printed biodegradable implant for long-acting in situ cancer therapy"

Ginevra Berardi, Instituto de Quimica Avanzada de Catalunya  (Spain), "Self-assembled PEG-SN38 nanostructure for colorectal cancer therapy"

Arianna Rinaldi, University of Modena and Reggio Emilia (Italy), "Stabilization of beta-Glucosidase in PLGA nanoparticles by Tween: formulation and activity studies"