AMYC-BIOMED 2021

3-5 November 2021 - Virtual Conference

PROGRAMME

3 November 2021

Analytical Chemistry

MORNING SESSION (9:15 - 12:25 CET)

Chairs:
Nunzia Iaccarino, University of Naples Federico II
Stefano Cinti, University of Naples Federico II


9:15 - 9:20
Institutional welcome: Prof. Angela Zampella, Dean of the Dept. of Pharmacy, University of Naples Federico II (Italy)


9:20 - 10:05
Plenary Lecture (40 + 5min Q/A): Prof. Luigi Mondello, University of Messina (Italy), "Innovative advanced analytical methods in biomedical sciences"


10:05 - 10:35
Keynote Speaker (25 + 5min Q/A): Prof. Bekzod Khakimov, University of Copenhagen (Denmark), "Human blood lipoprotein predictions from 1H NMR spectra: protocol, model performances and cage of covariance"


10:35 - 10:50

Oral Comm. 1 (12 + 3min Q/A)

Giovanni VenturaUniversity of Bari Aldo Moro (Italy), "AllerT: an automated workflow to identify putative food allergenic proteins of edible insects"


10:50 - 11:05

Oral Comm. 2 (12 + 3min Q/A)

Simona RanalloUniversity of Rome Tor Vergata (Italy) and UCSB (US), "Electrochemical DNA-based platform for the multiplexed detection of clinically relevant antibodies"


11:05 - 11:20
Break


11:20 - 11:35

Oral Comm. 3 (12 + 3min Q/A)

Susy Piovesana, Sapienza University of Rome (Italy), "Sulfopeptide enrichment and identification by liquid chromatography-mass spectrometry"


11:35 - 11:50

Oral Comm. 4 (12 + 3min Q/A)
Jerro Saidykhan, University of the West of England Bristol (UK), "Paper-based lateral flow device for measuring fibrinogen in human plasma", 


11:50 - 12:05

Oral Comm. 5 (12 + 3min Q/A)
Federico Fanti, University of Teramo (Italy), "Screening and quantitative analysis of short chain fatty acids by means SPE-HPLC-ESI-MS/MS"


12:05 - 12:25
4 x Short Comm. (Slide&Talk) (5min, no Q/A)

Vincenzo Mazzaracchio, University of Rome Tor Vergata (Italy), "A carbon Black-TiO2/KuQuinone screen-printed photoelectrochemical biosensor for ethanol detection in wine samples"

Giuseppe Arrabito, University of Palermo (Italy), "Ink depletion-free printing of phospholipids micro-patches"

Giuliana Siragusa, University of Verona (Italy), "Super SILAC-based mass spectrometry analysis of histone modifications in progressively de-differentiated cancer stem cells derived from pancreatic ductal adenocarcinoma cell lines"

Fulden Ulucan Karnak, Ege University (Turkey), "Nanobiosensor development for cancer diagnosis"


AFTERNOON SESSION  (14:30 - 17:15 CET)


14:30 - 15:00
Keynote Speaker (25 + 5min Q/A): 

Dr. Mariana Medina-Sánchez, Leibniz for Solid State and Materials Research Dresden (Germany), "Strain engineering for developing ultracompact biosensing devices"


15:00 - 15:15

Oral Comm. 6 (12 + 3min Q/A)
Marianna Rossetti, University of Rome Tor Vergata (Italy), "Design of electrochemical-active DNA modules harnessing the biomolecular confinement for the detection of antibodies"


15:15 - 15:30
Oral Comm. 7 (12 + 3min Q/A)
Andrea Capucciati, University of Pavia (Italy), "A rapid analytical method for determination of psychoactive substances: the case of Glaucine"


15:30 - 15:45

Oral Comm. 8 (12 + 3min Q/A)

Andrea Bonini, University of Pisa (Italy), "CRISPR/Cas12a based electrochemical bioassay for pathogenic bacteria detection involved in infectious diseases"


15:45 - 16:00
Break


16:00 - 16:15
Oral Comm. 9 (12 + 3min Q/A)

Carmela Maria Montone, Sapienza University of Rome (Italy), "Production and characterization of medium-sized and short antioxidant peptides from soy flour-simulated gastrointestinal hydrolysates"


16:15 - 16:30
Oral Comm. 10 (12 + 3min Q/A)

Simone Cavalera, University of Torino (Italy), "Design of multiplexing lateral flow immunoassay for detection and typing of foot-and-mouse disease virus using pan-reactive and serotype-specific monoclonal antibodies: evidence of a new hook effect"


16:30 - 16:45
Oral Comm. 11 (12 + 3min Q/A)

Jessica Brandi, University of Verona (Italy), "SWATH-MS analysis revealed mutant p53 secreted proteins influence on pancreatic cancer cells"


16:45 - 17:00
Oral Comm. 12 (12 + 3min Q/A)

Pavlos Nikolaou, University of Bologna (Italy), "PCR-free hepatitis B virus whole genome determination by electrogenerated chemiluminescence"


17:00 - 17:15
3 x Short Comm. "Slide&Talk" (5min, no Q/A)

Patryk Szymaszek, Cracow University of Technology (Poland), "Spectrophotometric investigation of the usefulness of novel pyridine derivatives to the role of luminescent sensors for the determination of albumin"

Andrea Cerrato, Sapienza University of Rome (Italy), "Solving the isomeric mass overlaps of phosphocholine-containing lipids in negative ionization mass spectrometry by buffer modification workflow"

Claudio Ignazio Santo, University of Bologna (Italy), "Electrochemiluminescent biosensor on BDD electrode"

4 November 2021

Medicinal Chemistry

MORNING SESSION (9:30 - 12:30 CET)

Chairs:
Stefano Tomassi, University of Naples Federico II
Sveva Pelliccia, University of Naples Federico II


9:30 - 10:15
Plenary Lecture (40 + 5min Q/A): Prof. Amedeo Caflisch, University of Zurich (Switzerland), "1,4,9-Triazaspiro[5.5]undecan-2-one derivatives as potent and selective METTL3 inhibitors"


10:15 - 10:45
Keynote Speaker (25 + 5min Q/A): Prof. Nir London, Weizmann Research Institute (Israel), "Teaching acrylamides new tricks"


10:45 - 11:00
Oral Comm. 1 (12 + 3min Q/A)

Giulio Poli, University of Pisa (Italy), "Novel cell-active PIN1 inhibitor identified through pharmacophore-driven virtual screening"


11:00 - 11:15
Oral Comm. 2 (12 + 3min Q/A)

Simona Musella, University of Salerno (Italy), "Design, Synthesis and biological evaluation of a dual acting SARS-CoV-2 proteases inhibitor agent"

11:15 - 11:30
Break


11:30 - 11:45
Oral Comm. 3 (12 + 3min Q/A)

Antonella Messore, Sapienza University of Rome (Italy), "Discovery of non-DKA derivatives inhibitors of the HIV-1 Ribonuclease H function of reverse transcriptase"


11:45 - 12:00
Oral Comm. 4 (12 +3min Q/A)

Piermichele Kobauri, University of  Groningen (Netherlands), "Rational design of light-controlled bioactive compounds for photopharmacology"


12:00 - 12:15
Oral Comm. 5 (12 + 3min Q/A)

Carmen Cerchia, University of Naples Federico II (Italy), "Sulfonimide and amide derivatives as novel PPAR-alpha  antagonists"


12:15 - 12:30
3 x Short Comm. "Slide&Talk" (5min, no Q/A)

Lorenzo Baldini, University of Firenze (Italy), "Design of dual peptidomimetic gelatinase/integrin inhibitors for tumor angiogenesis targeting"

Sara La Manna, University of Naples Federico II (Italy), "New SOCS1 cyclic peptidomimetics: from engineering to functional evaluation"
Diego Garcia Jiminez, University of Torino (Italy), "PROTACs: solubility and computed polarity"


AFTERNOON SESSION (14:30 - 17:15 CET)


14:30 - 15:00
Keynote Speaker (25 + 5min Q/A):

Prof. Angela Russell, University of Oxford (UK), "Cures from within: can we use chemistry to teach the body to heal itself?"


15:00 - 15:15
Oral Comm. 6 (12 + 3min Q/A)

Ottavia Bellotto, University of Trieste (Italy), "Supramolecular hydrogels from uncapped short dipeptides: heterochirality and halogenation as tools to inspire self-assembly"


15:15 - 15:30
Oral Comm. 7 (12 + 3min Q/A)

Sebastiano Intagliata, University of Catania (Italy), "New 5-fluorouracil and heme oxygenase 1 inhibitor mutual prodrugs with in vitro anticancer activity towards colon cancer cells"


15:30 - 15:45
Oral Comm. 8 (12 + 3min Q/A)

Alessandra Benassi, University of Pavia (Italy), "Photoactivatable V-shaped bifunctional quinone methide precursors as a new class of selective G-quadruplex alkylating agents"


15:45 - 16:00
Break


16:00 - 16:15
Oral Comm. 9 (12 + 3min Q/A)

Francesco Merlino, University of Naples Federico II (Italy), "Alpha-helix-inspired stapling of temporin-like peptides: new antimicrobial agents to challenge the antibiotic resistance"


16:15 - 16:30
Oral Comm. 10 (12 + 3min Q/A)

Lidia Ciccone, University of Pisa (Italy), "Multifunctional compounds inspired by natural derivatives as antioxidant agents and ALR2 inhibitors"


16:30 - 16:45

Oral Comm. 11 (12 + 3min Q/A)
Francesco Fiorentino, Sapienza University of Rome (Italy), "Drug discovery meets native mass spectrometry: unravelling the modulation of LPS transport proteins"


16:45 - 17:00
Oral Comm. 12 (12 + 3min Q/A)

Sara Battista, University of L' Aquila (Italy), "Preparation of structurally related liposomes and investigation of their physicochemical properties, antibacterial activity and synergistic effect with antibiotics"


17:00 - 17:15
3 x Short Comm. "Slide&Talk" (5min, no Q/A)

Alice Della Valle, University of Chieti Gabriele D' Annunzio (Italy), "Synthesis and characterization of linear peptides analogues of endomorphine-2 and Met/Leu-enkephalin containing a Freidinger gamma-lactam"

Salvatore Galati, University of Pisa (Italy), "structure-based analysis of machine learning predictions for isoform-selective carbonic anhydrase inhibitors"
Giulia De Soricellis, University of Milan (Italy), "Bulkiness and tryptophan: the keystone for Pt(II) and Ir(III) complexes to hit the target of bioimaging and photodynamic therapy?"

5 November 2021
Pharmaceutical Technology & Drug Delivery

MORNING SESSION (9:30 - 12:30 CET)

Chairs:

Claudia Conte, University of Naples Federico II

Gabriella Costabile, University of Naples Federico II


9:30 - 10:15

Plenary Lecture (40 + 5min Q/A): Prof. Cameron Alexander, University of Nottingham (UK), "Polymer therapeutics - from oncology to vaccines"


10:15 - 10:45

Keynote Speaker (25 + 5min Q/A): Prof. Maria de la Fuente Freire,

Oncomet Oncologia Médica Traslacional (Spain), "DIVERSA technologies, from the idea to the market"


10:45 - 11:00

Oral Comm. 1 (12 + 3min Q/A)

Giulia Chindamo, University of Torino (Italy), "Curcumin-loaded anticancer lipid nanoparticles design to overcome multi-drug resistance in triple negative breast cancer"


11:00 - 11:15

Oral Comm. 2 (12 + 3min Q/A)

Giovanni Del Poggetto, IPCB-CNR (Italy), "PEGylated cationic nanoassemblies based on triblock copolymers to combine siRNA therapeutics with anticancer drugs"


11:15 - 11:30
Break


11:30 - 11:40

Sponsor Talk - Elsevier


11:40 - 11:55

Oral Comm. 3 (12 + 3min Q/A)

Carlo Diaferia, University of Naples Federico II (Italy), "Doxorubicin delivery mediated by peptide-based hydrogels and nanogels"


11:55 - 12:10
Oral Comm. 4 (12 + 3min Q/A)

Sameh El Sayed, University of Birmingham (UK), "Enzyme-degradable polyion-complex nanoparticles for antimicrobial delivery"


12:10 - 12:30

4 x Short Comm. "Slide&Talk" (5min, no Q/A)

Greta Avancini, University of Padova (Italy), "Mesenchymal stem cells membranes camouflaged TPCS2a nanoparticles for targeted photodynamic therapy"
Sara Demartis, University of Sassari (Italy), "Rose bengal loaded 3D printed biodegradable implant for long-acting in situ cancer therapy"
Ginevra Berardi, Instituto de Quimica Avanzada de Catalunya  (Spain), "Self-assembled PEG-SN38 nanostructure for colorectal cancer therapy"
Arianna Rinaldi, University of Modena and Reggio Emilia (Italy), "Stabilization of beta-Glucosidase in PLGA nanoparticles by Tween: formulation and activity studies"


AFTERNOON SESSION (14:30 - 17:15 CET)


14:30 - 15:00
Keynote Speaker (25 + 5min Q/A):

Dr. Dimitrios Lamprou, Queen's University Belfast (UK), "Transforming treatment through emerging drug delivery technologies"


15:00 - 15:15
Oral Comm. 5 (12 + 3min Q/A)

Vincenzo Taresco, University of Nottingham (UK), "Poly (glycerol adipate) (PGA), an enzymatically synthesised functionalizable polyester as a versatile drug delivery carrier"


15:15 - 15:30
Oral Comm. 6 (12 + 3min Q/A)

Anna Maria Maurelli, University of Bari Aldo Moro (Italy), "Improving liposome performance in oral delivery of hydrophobic molecules"


15:30 - 15:45
Oral Comm. 7 (12 + 3min Q/A)

Beatrice Simonis, Sapienza University of Rome (Italy), "Design of novel liposome formulations for the delivery across a human blood brain barrier model"


15:45 - 16:00
Break

16:00 - 16:10
Sponsor Talk - Editor Wiley

16:10 - 16:25
Oral Comm. 8 (12 + 3min Q/A)

Sofia Parrasia, University of Padova (Italy), "Brain delivery of a mitochondriotropic inhibitor of the potassium channel Kv1.3: conjugation with peptides targeting BBB"


16:25 - 16:40

Oral Comm. 9 (12 + 3min Q/A)
Manish KumarMadhav University (India), "Development and optimization of drug-loaded nanoemulsion system by phase inversion temperature (PIT) method using Box-Behnken design"


16:40 - 16:55

Oral Comm. 10 (12 + 3 Q/A)
Mattia Tiboni, University of Urbino Carlo Bo (Italy), "Nanomedicine manufacturing: How 3D printing could widen the accessibility to microfluidics"

16:55 - 17:10

3 x Short Comm. "Slide&Talk" (5min, no Q/A)

Kriti Shukla, University of California Los Angeles (US), "The efficacy of simvastatin in preventing metastasis of Renal Cell Carcinoma (RCC) in a chicken chorioallantoic membrane (CAM) model"
Valentina Del Genio, University of Naples Federico II (Italy), "On demand nanofibers for cancer"
Maddalena Sguizzato, University of Ferrara (Italy), "Topical application of alpha-tocopherol-containing lipid nanoparticles: skin protection against pollutants"


17:10-17:15

AMYC-BIOMED Committee, Closing remarks, see you next year... in Naples!